Hi Madhur, the OS of the deployment where you host the autoupdate registry won't affect which operating systems osquery and Fleet support via the osqueryd agent. However, we want to inform you that you will need a subscription to Fleet Premium in order to use self-hosted autoupdates, which is a paid feature and only available with a Fleet Premium up to your licensed number of hosts. Otherwise, if your organization would prefer to stick to Fleet Free, you can use Fleet's provided autoupdates, or manage updates yourself using a configuration management tool.
If you are interested, you can view the pricing page for more information.
fleetdm.com/pricing